OncoTargets and Therapy (May 2024)

Scalp Metastasis After Breast Cancer Surgery: A Case Report

  • Wu J,
  • Zhang W,
  • Zhang H,
  • Lu X,
  • Luan B,
  • Yang Q,
  • Chen L,
  • Chen W,
  • Ge F

Journal volume & issue
Vol. Volume 17
pp. 411 – 419

Abstract

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Jingxuan Wu,1,2,* Wenzhu Zhang,1,2,* Hong Zhang,1,2,* Xingjia Lu,1,2,* Biqing Luan,1,2,* Qizhi Yang,1,2,* Liang Chen,1,* Wenlin Chen,3,* Fei Ge1,* 1Department of Breast Surgery, First Affiliated Hospital of Kunming Medical University, Kunming, 650000, People’s Republic of China; 2No. 1 School of Clinical Medicine, Kunming Medical University, Kunming, 650000, People’s Republic of China; 3Third Department of Breast Surgery, The Third Affiliated Hospital of Kunming Medical University, Kunming, 650000, People’s Republic of China*These authors contributed equally to this workCorrespondence: Fei Ge, Department of Breast Surgery, First Affiliated Hospital of Kunming Medical University, Kunming, 650000, People’s Republic of China, Email [email protected] Wenlin Chen, Third Department of Breast Surgery, The Third Affiliated Hospital of Kunming Medical University, Kunming, 650000, People’s Republic of China, Email [email protected]: Breast cancer is one of the most common malignant tumors affecting women worldwide. Breast cancer is a complex disease characterized by abnormal growth of cells in the breast tissue. Metastasis, the spread of cancer cells from the primary tumor site to distant organs, is a major challenge in the management of breast cancer. Although metastasis to distant sites is a well-known feature of breast cancer, scalp involvement is relatively rare. The occurrence of scalp metastasis signifies an advanced stage of the disease. The 51-year-old female discovered a firm, painless mass in her right breast that had been there for two years. It had been pricking for a month, and the biopsy revealed that the mass was invasive carcinoma of the right breast. Imaging tests suggested that the tumor was malignant. Adjuvant endocrine therapy and postoperative adjuvant chemotherapy were administered following a modified radical resection for breast cancer. Eleven months later, radiation treatment and replace endocrine therapy was used. 32 months following surgery, a scalp tumor was discovered; a pathology biopsy verified the origin of the breast cancer; three months later, bone, brain, and visceral metastases were discovered. After that, she received oral capecitabine treatment and was admitted into the hospital for advanced rescue treatment. She is currently in the disease stability state, her disease is effectively managed, and no new metastatic lesions have been discovered.Keywords: breast cancer, scalp metastasis, chemotherapy, radiotherapy, endocrine therapy, case report

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