A facile synthesis of novel series (Z)-2-((4-oxo-5-(thiophen-2-ylmethylene)-4,5-dihydrothiazol-2-yl)amino) substituted acid

Abstract

A new effective approach to the synthesis of some novel series of (Z)-2-((4-oxo-5-(thiophen-2-ylmethylene)-4,5-dihydrothiazol-2-yl)amino) substituted acid is reported at room temperature, less reaction time with good to excellent yields.

Keywords

• Knoevenagel condensation
• 2-Thioxothiazolidin-4-one
• Thiophene-2-carbaldehyde
• Amino acids