A Rare Cause of Hypercalcemia in Childhood; Parathyroid Adenoma: Case Report and Review of the Literature

Abstract

Hyperparathyroidism is very rare in children (incidence of 2-5 in 100 000) and occurs predominantly in adults (incidence of 1 in 1000). It is caused by increased synthesis of parathormone (PTH) by one or more pathologically effected parathyroid glands. HPT symptoms are usually non-specific and hypercalcemia may only be episodic in early period and these characteristics are the causes of late recognition and diagnosis of pediatric HPT which can culminate with end-organ damage. At the time of the diagnose 73-94% of PHPT cases in young patients are recognised as a symptomatic, and end-organ involvement, such as nephrocalcinosis, nephrolithiasis, acute pancreatitis, or bone involvement is not rare which is highly related to the prognosis. Therefore, early recognition and evaluation of symptoms would give a chance to prevent negative outcomes. In this case report we describe an incidentally diagnosed parathyroid adenoma in 11 year old asymptomatic male patient with no end-organ involvement.

Keywords

• Hypercalcemia
• hyperparathyroidism
• parathyroid adenoma