Arabian Journal of Chemistry (Feb 2017)

Solvent-free synthesis of α-aminophosphonates: Cellulose-SO3H as an efficient catalyst

  • Krishnammagari Suresh Kumar,
  • Balam Satheesh Krishna,
  • Chinnapareddy Bhupendra Reddy,
  • Mudumala Veera Narayana Reddy,
  • Cirandur Suresh Reddy

DOI
https://doi.org/10.1016/j.arabjc.2012.09.009
Journal volume & issue
Vol. 10, no. S1
pp. S368 – S375

Abstract

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α-Aminophosphonates possess a broad range of applications ranging from agrochemistry to medicine. We developed an efficient and eco-friendly Cellulose-SO3H catalyzed one-pot synthesis of α-aminophosphonates by three-component, room temperature reaction of an aldehyde, an amine and dialkylphosphite under solvent-free conditions. The major advantages of the present method are simple experimentation, use of inexpensive and eco-friendly reusable catalyst with good yields and short reaction times.

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