Application of alanine dosimetry in dose assessment for ocular melanoma patients undergoing proton radiotherapy – preliminary results
Mierzwińska Gabriela,
Kłodowska Magdalena,
Michalec Barbara,
Pędracka Anna,
Rydygier Marzena,
Swakoń Jan,
Waligórski Michael P. R.
Affiliations
Mierzwińska Gabriela
The Henryk Niewodniczański Institute of Nuclear Physics of the Polish Academy of Sciences, 152 Radzikowskiego Str., 31-342 Krakow, Poland, Tel.: +48 12 662 8327, Fax: +48 12 662 0866
Kłodowska Magdalena
Institute of Nuclear Physics of the Polish Academy of Sciences, 152 Radzikowskiego Str., 31-342 Krakow, Poland, Tel.: +48 12 662 8327
Michalec Barbara
The Henryk Niewodniczański Institute of Nuclear Physics of the Polish Academy of Sciences, 152 Radzikowskiego Str., 31-342 Krakow, Poland, Tel.: +48 12 662 8327, Fax: +48 12 662 0866
Pędracka Anna
The Henryk Niewodniczański Institute of Nuclear Physics of the Polish Academy of Sciences, 152 Radzikowskiego Str., 31-342 Krakow, Poland, Tel.: +48 12 662 8327, Fax: +48 12 662 0866
Rydygier Marzena
The Henryk Niewodniczański Institute of Nuclear Physics of the Polish Academy of Sciences, 152 Radzikowskiego Str., 31-342 Krakow, Poland, Tel.: +48 12 662 8327, Fax: +48 12 662 0866
Swakoń Jan
The Henryk Niewodniczański Institute of Nuclear Physics of the Polish Academy of Sciences, 152 Radzikowskiego Str., 31-342 Krakow, Poland, Tel.: +48 12 662 8327, Fax: +48 12 662 0866
Waligórski Michael P. R.
The Henryk Niewodniczański Institute of Nuclear Physics of the Polish Academy of Sciences, 152 Radzikowskiego Str., 31-342 Krakow, Poland and Centre of Oncology, Maria Skłodowska-Curie Memorial Institute, Krakow Branch, 11 Garncarska Str., 31-115 Krakow, Poland
Basing on alanine solid state/electron paramagnetic resonance (EPR) dosimetry, a supplementary method of cumulatively recording the therapeutic dose received by ocular cancer patients undergoing fractionated proton radiotherapy is proposed. By applying alanine dosimetry during the delivery of consecutive fractions, the dose received within each fraction can be read out by EPR spectrometry and a final permanent cumulative record of the total dose delivered obtained. The dose response of the alanine detector was found to be practically independent on its position within the extended proton Bragg peak region. Dose measurements based on entrance dose recorded in proton beams individually formed for each patient are presented. The described method will be applied as a complementary Quality Assurance procedure for patients undergoing proton radiotherapy at the Institute of Nuclear Physics, Polish Academy of Sciences, Krakow, Poland (IFJ PAN).
