Structure and Antioxidant Activity of Polyphenols Derived from Propolis
Anna Kurek-Górecka,
Anna Rzepecka-Stojko,
Michał Górecki,
Jerzy Stojko,
Marian Sosada,
Grażyna Świerczek-Zięba
Affiliations
Anna Kurek-Górecka
Silesian Medical College in Katowice, Mickiewicza 29, Katowice 40-085, Poland
Anna Rzepecka-Stojko
Department of Pharmaceutical Chemistry, School of Pharmacy with the Division of Laboratory Medicine, Medical University of Silesia, Jagiellońska 4, Sosnowiec 41-200, Poland
Michał Górecki
Department of Drug Technology, School of Pharmacy with the Division of Laboratory Medicine, Medical University of Silesia, Jedności 8, Sosnowiec 41-200, Poland
Jerzy Stojko
Department of Hygiene, Bioanalysis and Environmental Studies, School of Pharmacy with the Division of Laboratory Medicine, Medical University of Silesia, Kasztanowa 3A, Sosnowiec 41-200, Poland
Marian Sosada
Department of Drug Technology, School of Pharmacy with the Division of Laboratory Medicine, Medical University of Silesia, Jedności 8, Sosnowiec 41-200, Poland
Grażyna Świerczek-Zięba
Silesian Medical College in Katowice, Mickiewicza 29, Katowice 40-085, Poland
Propolis is a potential source of natural antioxidants such as phenolic acids and flavonoids. Its wide biological effects have been known and used since antiquity. In the modern world natural substances are sought which would be able to counteract the effects of antioxidative stress, which underlies many diseases, such as cancer, diabetes and atherosclerosis. This paper aims to present the antioxidative activity of phenolic acids and flavonoids present in Polish propolis and the relationship between their chemical structure and antioxidative activity influencing its medicinal properties. Data concerning the biological activity of propolis are summarized here, including its antibacterial, anti-inflammatory, anticarcinogenic, antiatherogenic, estrogenic effects, as well as AIDS- counteracting and reparative-regenerative function.
