Nanomaterials (May 2019)

Laser-Synthesized SERS Substrates as Sensors toward Therapeutic Drug Monitoring

  • Matteo Tommasini,
  • Chiara Zanchi,
  • Andrea Lucotti,
  • Alessandro Bombelli,
  • Nicolò S. Villa,
  • Marina Casazza,
  • Emilio Ciusani,
  • Ugo de Grazia,
  • Marco Santoro,
  • Enza Fazio,
  • Fortunato Neri,
  • Sebastiano Trusso,
  • Paolo M. Ossi

DOI
https://doi.org/10.3390/nano9050677
Journal volume & issue
Vol. 9, no. 5
p. 677

Abstract

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The synthesis by pulsed laser ablation and the characterization of both the surface nanostructure and the optical properties of noble metal nanoparticle-based substrates used in Surface Enhanced Raman Spectroscopy are discussed with reference to application in the detection of anti-epileptic drugs. Results on two representative drugs, namely Carbamazepine and Perampanel, are critically addressed.

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