Teratogenic and Embryocidal Effects of Zidovudine (AZT) in Sprague-Dawley Rats

Affiliations

James T. Christmas: Division of Prenatal Diagnosis, Department of Obstetrics & Gynecology, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas 75235-9032, TX, USA
Bertis B. Little: Division of Prenatal Diagnosis, Department of Obstetrics & Gynecology, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas 75235-9032, TX, USA
Kraig A. Knoll: Division of Prenatal Diagnosis, Department of Obstetrics & Gynecology, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas 75235-9032, TX, USA
Roger E. Bawdon: Division of Prenatal Diagnosis, Department of Obstetrics & Gynecology, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas 75235-9032, TX, USA
Larry C. Gilstrap III: Division of Prenatal Diagnosis, Department of Obstetrics & Gynecology, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas 75235-9032, TX, USA

Abstract

Objective: The purpose of the present investigation was to analyze the effets of zidovudine on the postimplantation embryo and fetus.

ISSN: 1064-7449 (Print); 1098-0997 (Online)
Publisher: Wiley
Country of publisher: United Kingdom
LCC subjects: Medicine: Gynecology and obstetrics; Medicine: Internal medicine: Infectious and parasitic diseases
Website: https://onlinelibrary.wiley.com/journal/7281