Marine Drugs (Sep 2015)

Polysaccharide Constituents of Three Types of Sea Urchin Shells and Their Anti-Inflammatory Activities

  • Heng Jiao,
  • Xiaohui Shang,
  • Qi Dong,
  • Shuang Wang,
  • Xiaoyu Liu,
  • Heng Zheng,
  • Xiaoling Lu

DOI
https://doi.org/10.3390/md13095882
Journal volume & issue
Vol. 13, no. 9
pp. 5882 – 5900

Abstract

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As a source of potent anti-inflammatory traditional medicines, the quantitative chromatographic fingerprints of sea urchin shell polysaccharides were well established via pre-column derivatization high performance liquid chromatography (HPLC) analysis. Based on the quantitative results, the content of fucose and glucose could be used as preliminary distinguishing indicators among three sea urchin shell species. Besides, the anti-inflammatory activities of the polysaccharides from sea urchin shells and their gonads were also determined. The gonad polysaccharide of Anthocidaris crassispina showed the most potent anti-inflammatory activity among all samples tested.

Keywords