Cedecea Davisae Bacteraemia after Tocilizumab Usage for Coronavirus Disease-2019 Treatment

Abstract

Cedecea davisae (C. davisae) is a Gram-negative, non-sporulating, motile rod-shaped bacterium of the Enterobacteriaceae family. Cedecea are new members of the Enterobacteriaceae family. Because of their inherent resistance to some antibiotics, the clinical response could be unpredictable, making the management of Cedecea infection challenging in immunocompromised patients. They have rarely been reported as causes of invasive infection. Cedecea can cause opportunistic infections in elderly patients. To the best of our knowledge, only 13 cases of C. davisae bacteraemia have been reported in literature. In this article, we report a case of C. davisae bacteraemia developed after the usage of tocilizumab for coronavirus disease-2019 treatment. A brief review of the literature is also presented in this article.

Keywords

• covid-19
• tocilizumab
• cedecea davisae
• sepsis
• bacteraemia