MULTIPARAMETRIC ELASTOGRAPHY – PRINCIPLES OF INDIVIDUAL SELECTION IN THE DIFFUSE LIVER DISEASES

Abstract

Aim of the study. Assessment of the capacity of multiparametric elastography (MPE) in the individual selection in diffuse liver diseases. Material and methods. A survey of 235 patients with diffuse liver diseases: 128 (54,5%) men and 107 (45,5%) women. The first group included 64 (27,2%) the patient with steatogepatitis, second – 97 (41,3%) with hepatitis, third – 74 (31,5%) with cirrhosis of the liver. Obligatory examination: transient elastography, compression elastography, elastography with endosonography, shear way elastography. Results. The initial examination of patients the results of the diagnostic accuracy sensitivity and specificity of all types of elastography: AUROC 0,461 to 0,987. Dynamic monitoring of patients to comply with medical advice: AUROC from 0,829 to is 0,997, who did not follow recommendations – 0,775 to 0,840. It helped to introduce the concept of multiparametric elastography (MPE). Conclusions. MPE can be considered as a universal tool for screening liver fibrosis both at the initial stage and in the process of dynamic observation.

Keywords

• multiparametric elastography
• diffuse liver diseases