Communications Biology (Sep 2022)

Construction of a trio-based structural variation panel utilizing activated T lymphocytes and long-read sequencing technology

  • Akihito Otsuki,
  • Yasunobu Okamura,
  • Noriko Ishida,
  • Shu Tadaka,
  • Jun Takayama,
  • Kazuki Kumada,
  • Junko Kawashima,
  • Keiko Taguchi,
  • Naoko Minegishi,
  • Shinichi Kuriyama,
  • Gen Tamiya,
  • Kengo Kinoshita,
  • Fumiki Katsuoka,
  • Masayuki Yamamoto

DOI
https://doi.org/10.1038/s42003-022-03953-1
Journal volume & issue
Vol. 5, no. 1
pp. 1 – 12

Abstract

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Long-read sequencing on activated T-cells from a sample of 333 Japanese individuals (representing 111 parent-offspring trios) provides a useful reference dataset of structural variation in the Japanese population.