Laryngeal gigant cell tumor

Abstract

Giant cell tumors (GCT) are usually benign, typically found in the epiphyseal area of long bones, affect individuals in the third decade, and have a slight female predilection. GCT represent about 4% to 9.5% of all bone tumors and 20% of all benign ones. Approximately 2% of all GCT occur in the head and neck region. However, primary laryngeal GCT is an infrequent entity, with 43 cases reported to date. Therefore, the present study aimed to report an issue of laryngeal GCT in a young male patient. Given the uncertainty of clinical and radiological distinction between the wide variety of differential diagnoses, histopathological examination is indispensable for a definitive diagnosis and therapeutic management. The treatment of GCT is controversial. However, currently, the literature supports surgical management. The incidence of GCT is not a common situation in medical practice, and the diversity of differential diagnoses is quite broad, which may lead the physician to suspect other diseases that affect the larynx. GCT is rarely considered among the diagnostic hypotheses, its incidence is sporadic, and management data must be studied.

Keywords

• giant cell tumors
• larynx
• dysphonia