Revista da Sociedade Brasileira de Medicina Tropical ()

The role of the Xpert MTB/RIF assay among adolescents suspected of pulmonary tuberculosis in Rio de Janeiro, Brazil

  • Thania Luiza de Andrade Sieiro,
  • Rafaela Baroni Aurílio,
  • Elizabeth Cristina C. Soares,
  • Silvia S. Chiang,
  • Clemax Couto Sant´Anna

DOI
https://doi.org/10.1590/0037-8682-0298-2017
Journal volume & issue
Vol. 51, no. 2
pp. 234 – 236

Abstract

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Abstract INTRODUCTION The teste rápido molecular para tuberculose (TRM-TB) was introduced in 2014 in Brazil for tuberculosis screening. However, its role in adolescents in Brazil has not been studied. METHODS A descriptive study of adolescents with suspected tuberculosis using National Laboratory software. RESULTS Of 852 (15.4%) suspected cases, 131 were positive by TRM-TB and 2% were resistant to rifampicin. Among TRM-TB-positive cases, 105 (91.4%) were culture-positive. Sixty-four of 96 samples were sensitive to rifampicin by TRM-TB; 11 were resistant to other drugs by drug sensitivity test (DST). CONCLUSIONS Among suspected cases, 16% were diagnosed by TRM-TB, of which 17% were drug-resistant by DST.

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