DNA-templated synthesis of biomimetic cell wall for nanoencapsulation and protection of mammalian cells

Peng Shi; Nan Zhao; James Coyne; Yong Wang

doi:10.1038/s41467-019-10231-y

Nature Communications (May 2019)

DNA-templated synthesis of biomimetic cell wall for nanoencapsulation and protection of mammalian cells

Peng Shi,
Nan Zhao,
James Coyne,
Yong Wang

Affiliations

Peng Shi: Department of Biomedical Engineering, The Pennsylvania State University, University Park
Nan Zhao: Department of Biomedical Engineering, The Pennsylvania State University, University Park
James Coyne: Department of Biomedical Engineering, The Pennsylvania State University, University Park
Yong Wang: Department of Biomedical Engineering, The Pennsylvania State University, University Park

DOI: https://doi.org/10.1038/s41467-019-10231-y
Journal volume & issue: Vol. 10, no. 1
pp. 1 – 11

Abstract

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The creation of protective barriers around cells is of interest for a range of applications. Here, the authors report on the creation of DNA templated alginate-polylysine biomimetic cell walls for encapsulating and shielding cells, demonstrating protection against physical assaults and immune reactions.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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