Knowledge mobilization activities to support decision-making by youth, parents, and adults using a systematic and living map of evidence and recommendations on COVID-19: protocol for three randomized controlled trials and qualitative user-experience studies
Rana Charide,
Lisa Stallwood,
Matthew Munan,
Shahab Sayfi,
Lisa Hartling,
Nancy J. Butcher,
Martin Offringa,
Sarah Elliott,
Dawn P. Richards,
Joseph L. Mathew,
Elie A. Akl,
Tamara Kredo,
Lawrence Mbuagbaw,
Ashley Motillal,
Ami Baba,
Matthew Prebeg,
Jacqueline Relihan,
Shannon D. Scott,
Jozef Suvada,
Maicon Falavigna,
Miloslav Klugar,
Tamara Lotfi,
Adrienne Stevens,
Kevin Pottie,
Holger J. Schünemann
Affiliations
Rana Charide
Michael G. DeGroote Cochrane Canada and McMaster GRADE Centres, Department of Health Research Methods, Evidence and Impact, McMaster University
Lisa Stallwood
Child Health Evaluative Sciences, The Hospital for Sick Children Research Institute
Matthew Munan
Alberta Research Centre for Health Evidence, Department of Pediatrics, Faculty of Medicine and Dentistry, University of Alberta
Shahab Sayfi
Schulich School of Medicine & Dentistry, Western University
Lisa Hartling
Alberta Research Centre for Health Evidence, Department of Pediatrics, Faculty of Medicine and Dentistry, University of Alberta
Nancy J. Butcher
Child Health Evaluative Sciences, The Hospital for Sick Children Research Institute
Martin Offringa
Child Health Evaluative Sciences, The Hospital for Sick Children Research Institute
Sarah Elliott
Alberta Research Centre for Health Evidence, Department of Pediatrics, Faculty of Medicine and Dentistry, University of Alberta
Dawn P. Richards
Five02 Labs Inc
Joseph L. Mathew
Postgraduate Institute of Medical Education and Research
Elie A. Akl
Michael G. DeGroote Cochrane Canada and McMaster GRADE Centres, Department of Health Research Methods, Evidence and Impact, McMaster University
Tamara Kredo
Cochrane South Africa, South African Medical Research Council
Lawrence Mbuagbaw
Michael G. DeGroote Cochrane Canada and McMaster GRADE Centres, Department of Health Research Methods, Evidence and Impact, McMaster University
Ashley Motillal
Michael G. DeGroote Cochrane Canada and McMaster GRADE Centres, Department of Health Research Methods, Evidence and Impact, McMaster University
Ami Baba
Child Health Evaluative Sciences, The Hospital for Sick Children Research Institute
Matthew Prebeg
Centre for Addiction and Mental Health
Jacqueline Relihan
Centre for Addiction and Mental Health
Shannon D. Scott
Faculty of Nursing, University of Alberta
Jozef Suvada
Departments of Science and International Studies, St. Elizabeth University of Public Health and Social Science
Maicon Falavigna
National Institute for Health Technology Assessment, Federal University of Rio Grande do Sul
Miloslav Klugar
Czech National Centre for Evidence-Based Healthcare and Knowledge Translation (Cochrane Czech Republic, Czech EBHC: JBI Centre of Excellence, Masaryk University GRADE Centre), Institute of Biostatistics and Analyses, Faculty of Medicine, Masaryk University
Tamara Lotfi
Michael G. DeGroote Cochrane Canada and McMaster GRADE Centres, Department of Health Research Methods, Evidence and Impact, McMaster University
Adrienne Stevens
Centre for Immunization Readiness, Public Health Agency of Canada
Kevin Pottie
Schulich School of Medicine & Dentistry, Western University
Holger J. Schünemann
Michael G. DeGroote Cochrane Canada and McMaster GRADE Centres, Department of Health Research Methods, Evidence and Impact, McMaster University
Abstract Introduction The COVID-19 pandemic underlined that guidelines and recommendations must be made more accessible and more understandable to the general public to improve health outcomes. The objective of this study is to evaluate, quantify, and compare the public’s understanding, usability, satisfaction, intention to implement, and preference for different ways of presenting COVID-19 health recommendations derived from the COVID-19 Living Map of Recommendations and Gateway to Contextualization (RecMap). Methods and analysis This is a protocol for a multi-method study. Through an online survey, we will conduct pragmatic allocation-concealed, blinded superiority randomized controlled trials (RCTs) in three populations to test alternative formats of presenting health recommendations: adults, parents, and youth, with at least 240 participants in each population. Prior to initiating the RCT, our interventions will have been refined with relevant stakeholder input. The intervention arm will receive a plain language recommendation (PLR) format while the control arm will receive the corresponding original recommendation format as originally published by the guideline organizations (standard language version). Our primary outcome is understanding, and our secondary outcomes are accessibility and usability, satisfaction, intended behavior, and preference for the recommendation formats. Each population’s results will be analyzed separately. However, we are planning a meta-analysis of the results across populations. At the end of each survey, participants will be invited to participate in an optional one-on-one, virtual semi-structured interview to explore their user experience. All interviews will be transcribed and analyzed using the principles of thematic analysis and a hybrid inductive and deductive approach. Ethics and dissemination Through Clinical Trials Ontario, the Hamilton Integrated Research Ethics Board has reviewed and approved this protocol (Project ID: 3856). The University of Alberta has approved the parent portion of the trial (Project ID:00114894). Findings from this study will be disseminated through open-access publications in peer-reviewed journals and using social media. Trial registration Clinicaltrials.gov NCT05358990 . Registered on May 3, 2022
