Atypical Polypoid Adenomyoma of the Vagina: Follow Up and Subsequent Evolution: A Case Report and Update
Melinda Ildiko Mitranovici,
Ioan Emilian Oală,
Izabella Petre,
Marius Lucian Craina,
Silviana Narcisa Floruț,
Diana Maria Chiorean,
Iuliu Gabriel Cocuz,
Sabin Gligore Turdean,
Ovidiu Simion Cotoi,
Lucian Pușcașiu
Affiliations
Melinda Ildiko Mitranovici
Department of Obstetrics and Gynecology, Emergency County Hospital Hunedoara, 14 Victoriei Street, 331057 Hunedoara, Romania
Ioan Emilian Oală
Department of Obstetrics and Gynecology, Emergency County Hospital Hunedoara, 14 Victoriei Street, 331057 Hunedoara, Romania
Izabella Petre
Department of Obstetrics and Gynecology, Victor Babeș University of Medicine and Pharmacy, 2 Eftimie Murgu Sq, 300041 Timisoara, Romania
Marius Lucian Craina
Department of Obstetrics and Gynecology, Victor Babeș University of Medicine and Pharmacy, 2 Eftimie Murgu Sq, 300041 Timisoara, Romania
Silviana Narcisa Floruț
Department of Pathology, Emergency County Hospital Hunedoara, 14 Victoriei Street, 331057 Hunedoara, Romania
Diana Maria Chiorean
Department of Pathophysiology, George Emil Palade University of Medicine, Pharmacy, Science, and Technology of Târgu Mureș, 38 Gheorghe Marinescu Street, 540142 Târgu Mureș, Romania
Iuliu Gabriel Cocuz
Department of Pathophysiology, George Emil Palade University of Medicine, Pharmacy, Science, and Technology of Târgu Mureș, 38 Gheorghe Marinescu Street, 540142 Târgu Mureș, Romania
Sabin Gligore Turdean
Department of Pathophysiology, George Emil Palade University of Medicine, Pharmacy, Science, and Technology of Târgu Mureș, 38 Gheorghe Marinescu Street, 540142 Târgu Mureș, Romania
Ovidiu Simion Cotoi
Department of Pathophysiology, George Emil Palade University of Medicine, Pharmacy, Science, and Technology of Târgu Mureș, 38 Gheorghe Marinescu Street, 540142 Târgu Mureș, Romania
Lucian Pușcașiu
Department of Obstetrics, Gynecology County Emergency Hospital, University of Medicine and Pharmacty Targu Mures, 38 Gh. Marinescu Str., 540142 Targu Mures, Romania
Atypical polypoid adenomyoma (APA) is a rare tumor developed from a mix of cells of epithelial and mesenchymal origin. We present the case of an 84-year-old patient with atypical polypoid adenomyoma on the vaginal vault, after total hysterectomy with total adnexectomy for endometrial hyperplasia with atypia four years ago. Not following regular indicated gynecological appointments, the symptoms presented were vaginal bleeding and anemia. The importance of the case consists both in the unique way in which the adenomyoma appears on the vaginal vault and in the subsequent evolution of this pathology. After complete resection, it recurs in five months with a malignant transformation into carcinosarcoma. This fact shows that adenomas can turn not only into carcinomas but also the mesenchymal component can progress to sarcoma, a fact of exceptional rarity. Follow-up and accurate diagnosis are essential for proper management, which is a challenge anyway due to the lack of case studies.
