Epigenome-wide association study shows that smoking alters DNA methylation in blood cells triggering aggressive bone resorption of osteoclasts in vivo and in vitro

• Salah Eddine Masmoudi,
• Anaïs M.J. Møller,
• Jonas S. Madsen,
• Jean-Marie Delaissé,
• Bjarne W. Rasnussen,
• Qihua Tan,
• Kent Søe

Affiliations

Salah Eddine Masmoudi

Unit of Epidemiology- Biostatistics and Biodemography, Public Health- University of Southern Denmark, Odense, Denmark; Corresponding author.

Anaïs M.J. Møller

Clinical Cell Biology- Res. Unit of Pathology, Clinical Research- University of Southern Denmark, Odense, Denmark

Jonas S. Madsen

Lillebaelt Hospital- University Hospital of Southern Denmark, Biochemistry, Odense, Denmark

Jean-Marie Delaissé

Clinical Cell Biology- Res. Unit of Pathology, Clinical Research- University of Southern Denmark, Odense, Denmark

Bjarne W. Rasnussen

Odense University Hospital, Pathology, Odense, Denmark

Qihua Tan

Unit of Epidemiology- Biostatistics and Biodemography, Public Health- University of Southern Denmark, Odense, Denmark

Kent Søe

Clinical Cell Biology- Res. Unit of Pathology, Clinical Research- University of Southern Denmark, Odense, Denmark