Confronting Accelerating Global Antimicrobial Resistance and the Associated Increase in Deaths

Abstract

Although advances in contemporary medical care have broadened access to healthcare and extended the human life span, deaths resulting from antimicrobial-resistant pathogens continue to increase. This minireview summarizes the evidence that AI and machine learning, coupled with precision medicine and alternative therapies, such as repurposing non-antibiotic drugs and the use of bacteriophages, has promise to halt this advance.

Keywords

• antimicrobial resistance
• artificial intelligence
• global mortality
• bacteriophage therapy
• antimicrobials with unique mechanisms of action