Dataset and AI Workflow for Deep Learning Image Classification of Ulcerative Colitis and Colorectal Cancer

Abstract

Inflammatory bowel disease (IBD) is a chronic inflammatory condition of the gastrointestinal tract characterized by the deregulation of immuno-oncology markers. IBD includes ulcerative colitis and Crohn’s disease. Chronic active inflammation is a risk factor for the development of colorectal cancer (CRC). This technical note describes a dataset of histological images of ulcerative colitis, CRC (adenocarcinoma), and colon control. The samples were stained with hematoxylin and eosin (H&E), and immunohistochemically analyzed for LAIR1 and TOX2 markers. The methods used for collecting, processing, and analyzing scientific data, including this dataset, using convolutional neural networks (CNNs) and information about the dataset’s use are also described. This article is a companion to the manuscript “Ulcerative Colitis, LAIR1 and TOX2 Expression, and Colorectal Cancer Deep Learning Image Classification Using Convolutional Neural Networks”.

Keywords

• ulcerative colitis
• colorectal cancer
• adenocarcinoma
• artificial intelligence
• deep learning
• convolutional neural network