Saudi Endodontic Journal (Sep 2025)
Comparison of human pulpal dissolution and removal of smear layer by triton and Qmix 2 in 1 solution: An in vitro study
Abstract
Introduction: Triton, a newer irrigant, is a combination of sodium hypochlorite (NaOCl) with chelating agents. However, its role in endodontic irrigation needs to be explored in different ways. Therefore, this study aims to assess the pulp dissolution and smear layer removal of triton compared to 2.5% NaOCl + 17% ethyl diamine tetra acetic acid (EDTA) and Qmix 2 in 1 solution. Materials and Methods: A total of 108 extracted vital single-rooted human premolars, free of fractures, caries, or restorations, were collected following orthodontic extractions. Sixty extracted teeth were split, and pulp tissue was subjected to four groups (n = 15): distilled water (control), 2.5% NaOCl + 17% EDTA, Qmix 2 in 1, and Triton. Samples were exposed to irrigants for 5, 10, and 15 min, and tissue weight loss was measured. For smear layer removal, 48 specimens were decoronated, instrumented, and irrigated with the respective solutions. The smear layer was examined under a scanning electron microscope, and data were analyzed using one-way analysis of variance, post hoc Tukey tests (P ≤ 0.05). Results: Triton demonstrated the maximum pulpal tissue dissolving capability and removal of smear layer than Qmix, 2.5% NaOCl and 17% EDTA. Conclusion: Triton was found to be superior in dissolving the human pulpal tissue and eliminating the smear layer than Qmix, and a combination of 2.5% NaOCl and 17% EDTA.
Keywords