Nature Communications (Apr 2022)
SWI/SNF chromatin remodeler complex within the reward pathway is required for behavioral adaptations to stress
- Abdallah Zayed,
- Camille Baranowski,
- Anne-Claire Compagnion,
- Cécile Vernochet,
- Samah Karaki,
- Romain Durand-de Cuttoli,
- Estefani Saint-Jour,
- Soumee Bhattacharya,
- Fabio Marti,
- Peter Vanhoutte,
- Moshe Yaniv,
- Philippe Faure,
- Jacques Barik,
- Laurence Amar,
- François Tronche,
- Sébastien Parnaudeau
Affiliations
- Abdallah Zayed
- Sorbonne Université, Gene Regulation and Adaptive Behaviors, Neuroscience Paris-Seine, IBPS. CNRS UMR8246, INSERM
- Camille Baranowski
- Sorbonne Université, Gene Regulation and Adaptive Behaviors, Neuroscience Paris-Seine, IBPS. CNRS UMR8246, INSERM
- Anne-Claire Compagnion
- Sorbonne Université, Gene Regulation and Adaptive Behaviors, Neuroscience Paris-Seine, IBPS. CNRS UMR8246, INSERM
- Cécile Vernochet
- Sorbonne Université, Gene Regulation and Adaptive Behaviors, Neuroscience Paris-Seine, IBPS. CNRS UMR8246, INSERM
- Samah Karaki
- Sorbonne Université, Gene Regulation and Adaptive Behaviors, Neuroscience Paris-Seine, IBPS. CNRS UMR8246, INSERM
- Romain Durand-de Cuttoli
- Sorbonne Université, Neurophysiology and Behaviors, Neuroscience Paris-Seine, IBPS. CNRS UMR8246, INSERM, UPMC
- Estefani Saint-Jour
- Sorbonne Université, Neuronal Signaling and Gene Regulation, Neuroscience Paris-Seine, IBPS. CNRS UMR8246, INSERM, UPMC
- Soumee Bhattacharya
- Sorbonne Université, Gene Regulation and Adaptive Behaviors, Neuroscience Paris-Seine, IBPS. CNRS UMR8246, INSERM
- Fabio Marti
- Sorbonne Université, Neurophysiology and Behaviors, Neuroscience Paris-Seine, IBPS. CNRS UMR8246, INSERM, UPMC
- Peter Vanhoutte
- Sorbonne Université, Neuronal Signaling and Gene Regulation, Neuroscience Paris-Seine, IBPS. CNRS UMR8246, INSERM, UPMC
- Moshe Yaniv
- Developmental and Stem Cell Biology department, Pasteur Institute
- Philippe Faure
- Sorbonne Université, Neurophysiology and Behaviors, Neuroscience Paris-Seine, IBPS. CNRS UMR8246, INSERM, UPMC
- Jacques Barik
- Sorbonne Université, Gene Regulation and Adaptive Behaviors, Neuroscience Paris-Seine, IBPS. CNRS UMR8246, INSERM
- Laurence Amar
- Sorbonne Université, Gene Regulation and Adaptive Behaviors, Neuroscience Paris-Seine, IBPS. CNRS UMR8246, INSERM
- François Tronche
- Sorbonne Université, Gene Regulation and Adaptive Behaviors, Neuroscience Paris-Seine, IBPS. CNRS UMR8246, INSERM
- Sébastien Parnaudeau
- Sorbonne Université, Gene Regulation and Adaptive Behaviors, Neuroscience Paris-Seine, IBPS. CNRS UMR8246, INSERM
- DOI
- https://doi.org/10.1038/s41467-022-29380-8
- Journal volume & issue
-
Vol. 13,
no. 1
pp. 1 – 18
Abstract
Repeated exposure to social stressors in rodents results in behavioural changes. Here the authors show that behavioural adaptations to stress are associated with nuclear organization changes through SWI/SNF chromatin remodeler in specific neuronal populations of the mesolimbic system.
