Abstract Amoebic liver abscess is common in children in developing countries due to lack of hygiene and sanitary conditions. Inferior vena cava thrombosis is a rare complication of this disease, with only a few cases reported in the literature, where this thrombus led to pulmonary thromboembolism. We report the case of a 7‐year‐old child with amoebic liver abscess who developed pulmonary thromboembolism and was promptly diagnosed and managed.