Proximal diabetic neuropathy (medical case)

Abstract

A medical case of a rare form of damage to the peripheral nervous system in diabetes, proximal diabetic amyotrophy (PDA), is described. PDA is characterized by asymmetric proximal lesions in the leg combined with neuropathic pain, muscle weakness and atrophy, mild sensation disorders, increased protein in the cerebrospinal fluid and severe disability. The etiopathogenesis is determined by immune-mediated lesions of vessels, nerves and nerve roots, peri-and microvasculitis, ischemia of the peripheral nervous system structures. Combination treatment with glucocorticoid medications, thioctic acid drugs (Berlithion®) normalization of glycemic profile and symptomatic treatment of neuropathic pain, resulted in a marked positive effect - decreased motor defects and pain, and significant regression of sensory disorders.

Keywords

• диабетическая полинейропатия
• диабетическая проксимальная амиотрофия
• препараты тиоктовой кислоты
• берлитион
• diabetic polyneuropathy
• proximal diabetic amyotrophy
• thioctic acid drugs
• berlithion