Quantitative dynamic contrast-enhanced parameters and intravoxel incoherent motion facilitate the prediction of TP53 status and risk stratification of early-stage endometrial carcinoma

Wang Hongxia; Yan Ruifang; Li Zhong; Wang Beiran; Jin Xingxing; Guo Zhenfang; Liu Wangyi; Zhang Meng; Wang Kaiyu; Guo Jinxia; Han Dongming

doi:10.2478/raon-2023-0023

Radiology and Oncology (Jun 2023)

Quantitative dynamic contrast-enhanced parameters and intravoxel incoherent motion facilitate the prediction of TP53 status and risk stratification of early-stage endometrial carcinoma

Wang Hongxia,
Yan Ruifang,
Li Zhong,
Wang Beiran,
Jin Xingxing,
Guo Zhenfang,
Liu Wangyi,
Zhang Meng,
Wang Kaiyu,
Guo Jinxia,
Han Dongming

Affiliations

Wang Hongxia: Department of MR, the First Affiliated Hospital of Xinxiang Medical University, Weihui, China
Yan Ruifang: Department of MR, the First Affiliated Hospital of Xinxiang Medical University, Weihui, China
Li Zhong: Department of MR, the First Affiliated Hospital of Xinxiang Medical University, Weihui, China
Wang Beiran: Department of MR, the First Affiliated Hospital of Xinxiang Medical University, Weihui, China
Jin Xingxing: Department of MR, the First Affiliated Hospital of Xinxiang Medical University, Weihui, China
Guo Zhenfang: Department of Neurology, the First Affiliated Hospital of Xinxiang Medical University, Weihui, China
Liu Wangyi: Department of MR, the First Affiliated Hospital of Xinxiang Medical University, Weihui, China
Zhang Meng: Department of MR, the First Affiliated Hospital of Xinxiang Medical University, Weihui, China
Wang Kaiyu: MR Research China, GE Healthcare, Beijing, China
Guo Jinxia: MR Research China, GE Healthcare, Beijing, China
Han Dongming: Department of MR, the First Affiliated Hospital of Xinxiang Medical University, Weihui, China

DOI: https://doi.org/10.2478/raon-2023-0023
Journal volume & issue: Vol. 57, no. 2
pp. 257 – 269

Abstract

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The aim of the study was to investigate the value of dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) and intravoxel incoherent motion (IVIM) in differentiating TP53-mutant from wild type, low-risk from non-low-risk early-stage endometrial carcinoma (EC).

Published in Radiology and Oncology

ISSN: 1581-3207 (Online)
Publisher: Sciendo
Country of publisher: Slovenia
LCC subjects: Medicine: Medicine (General): Medical physics. Medical radiology. Nuclear medicine
Website: https://sciendo.com/journal/RAON

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