Resveratrol Role in Autoimmune Disease—A Mini-Review
Ana Lígia de Brito Oliveira,
Valter Vinicius Silva Monteiro,
Kely Campos Navegantes-Lima,
Jordano Ferreira Reis,
Rafaelli de Souza Gomes,
Dávila Valentina Silva Rodrigues,
Silvia Letícia de França Gaspar,
Marta Chagas Monteiro
Affiliations
Ana Lígia de Brito Oliveira
Pharmaceutical Science Post-Graduation Program, Neuroscience and Cellular Biology Post Graduation Program, Faculty of Pharmacy, Federal University of Pará, Avenue Augusto Correa SN, Guamá, Pará 66075-110, Brazil
Valter Vinicius Silva Monteiro
School of Pharmacy, Health Science Institute, Federal University of Pará/UFPA, Avenue Augusto Correa SN, Guamá, Pará 66075-110, Brazil
Kely Campos Navegantes-Lima
Pharmaceutical Science Post-Graduation Program, Neuroscience and Cellular Biology Post Graduation Program, Faculty of Pharmacy, Federal University of Pará, Avenue Augusto Correa SN, Guamá, Pará 66075-110, Brazil
Jordano Ferreira Reis
School of Pharmacy, Health Science Institute, Federal University of Pará/UFPA, Avenue Augusto Correa SN, Guamá, Pará 66075-110, Brazil
Rafaelli de Souza Gomes
Pharmaceutical Science Post-Graduation Program, Neuroscience and Cellular Biology Post Graduation Program, Faculty of Pharmacy, Federal University of Pará, Avenue Augusto Correa SN, Guamá, Pará 66075-110, Brazil
Dávila Valentina Silva Rodrigues
School of Pharmacy, Health Science Institute, Federal University of Pará/UFPA, Avenue Augusto Correa SN, Guamá, Pará 66075-110, Brazil
Silvia Letícia de França Gaspar
School of Pharmacy, Health Science Institute, Federal University of Pará/UFPA, Avenue Augusto Correa SN, Guamá, Pará 66075-110, Brazil
Marta Chagas Monteiro
Pharmaceutical Science Post-Graduation Program, Neuroscience and Cellular Biology Post Graduation Program, Faculty of Pharmacy, Federal University of Pará, Avenue Augusto Correa SN, Guamá, Pará 66075-110, Brazil
Autoimmune diseases are still considered to be pressing concerns due the fact that they are leaders in death and disability causes worldwide. Resveratrol is a polyphenol derived from a variety of foods and beverages, including red grapes and red wine. Anti-inflammatory, antioxidant, and antiaging properties of resveratrol have been reported, and in some animal and human studies this compound reduced and ameliorated the progression of autoimmune diseases, such as rheumatoid arthritis, systemic lupus erythematosus, psoriasis, inflammatory bowel disease, and type 1 diabetes mellitus. Thus, this review aims to summarize and critically analyze the role of resveratrol in the modulation of several organ-specific or systemic autoimmune diseases.