Indian Journal of Ophthalmology (Jan 2014)
Collagen cross-linking in the treatment of pellucid marginal degeneration
- Ziad Hassan,
- Gabor Nemeth,
- Laszlo Modis,
- Eszter Szalai,
- Andras Berta
Affiliations
- Ziad Hassan
- Gabor Nemeth
- Laszlo Modis
- Eszter Szalai
- Andras Berta
- DOI
- https://doi.org/10.4103/0301-4738.109523
- Journal volume & issue
-
Vol. 62,
no. 3
pp. 367 – 370
Abstract
Pellucid marginal degeneration (PMD) is an uncommon cause of inferior peripheral corneal thinning disorder, characterized by irregular astigmatism. We analyzed a case of bilateral PMD patient and treated one eye with corneal collagen cross-linking (CXL) therapy. Corneal topography was characteristic for PMD. Visual acuity, slitlamp examinations, tonometry, and corneal thickness were observed. Simulated keratometric and topographic index values were detected with corneal topography. Uncorrected, LogMAR visual acuity has improved from +0.8 to +0.55 during the 6 months and +0.3 during the 8 months follow-up after CXL. Pachymetry values and intraocular pressure showed no changes. Keratometric values and topografic indexes disclosed no progression of the disease. CXL may postpone or eliminate the need of corneal transplantation in cases with PMD.
Keywords
- Clinical profile
- Indian population
- optic neuritis treatment trial
- optic neuritis
- Decompression of the orbit
- diplopia
- orbit
- thyroid exophthalmos
- thyroid ophthalmopathy
- Limbus incision
- subconjunctival incision
- sutureless manual small-incision cataract surgery
- wound construction
- Central retinal vein occlusion
- intravitrealbevacizumab
- intravitrealtriamcinolone acetonide
- macular edema
- Contrast sensitivity
- fixation
- microperimeter
- normative data
- retinal sensitivity
- Optical coherence tomography
- optic disc pit
- retinal detachment
- retinoschisis
- Homocysteine
- retinal vein occlusion
- visual impairment
- Diabetic macular edema
- monocyte chemoattractant protein-1
- soluble intracellular adhesion molecule-1
- vascular endothelial growth factor
- Compressive optic neuropathy
- humphrey visual field
- ischemic optic neuropathy
- multifocal visual evoked potential
- optic neuritis
- Age
- body mass index
- gender
- high density lipoprotein
- intraocular pressure
- lipid profiles
- total cholesterol
- triglyceride
- Capsular tension ring
- cataract
- intraocular lens
- myopia
- phacoemulsification
- posterior capsular opacification
- Ethnicity
- Indian
- macular thickness
- normative
- retinal nerve fiber layer
- Ocular torticollis
- superior oblique palsy
- surgery
- Barriers to follow-up
- pediatric cataract
- visual outcome
- Cataract
- intracameral mydriatic solution
- no preoperative mydriatic
- phacoemulsification
- Disc edema
- neem oil
- putamen
- toxin-induced encephalopathy
- Toxic Optic Neuropathy Secondary to Consumption of Neem Oil
- Absent thumb
- craniofacial defects
- limbal dermoid
- Nager syndrome
- Keratitis
- Rhodotorula sp
- Polymerase chain reaction
- Atypical
- cholesterol granuloma
- orbit
- Capsular block syndrome
- optic neuropathy
- phacoemulsification
- Haptic fracture
- posterior chamber intraocular lens fracture
- spontaneous fracture
- Bacterial conjunctivitis
- conjunctivitis
- gram negative diplococcus
- Neisseria sicca
- netilmicin
- Aspergillosis
- endophthalmitis
- vitrectomy
- voriconazole
- Eyelid retraction
- orbital infection
- orbital neonatal abscess
- neonatal abscess
- Dirofilaria
- intraocular dirofilaria
- worm
- Axenfeld-Rieger Syndrome
- anterior segment dysgenesis
- blepharophimosis ptosis epicanthus inversus syndrome
- glaucoma
- Actinic granuloma
- conjunctiva
- granuloma annulare
- necrobiosis lipoidica
- Internal limiting membrane
- macular hole
- optical coherence tomography
- re-surgery
- vitrectomy
- Ichthyosis follicularis
- alopecia and photophobia syndrome
- meibomian gland dysfunction
- ocular invovement
- Collagen cross-linking
- pellucid marginal degeneration
- Pentacam HR
