Nucleophilic functionalization of thianthrenium salts under basic conditions

Abstract

In recent years, S-(alkyl)thianthrenium salts have become an important means of functionalizing alcohol compounds. However, additional transition metal catalysts and/or visible light are required. Herein, a direct thioetherification/amination reaction of thianthrenium salts is realized under metal-free conditions. This strategy exhibits good functional-group tolerance, operational simplicity, and an extensive range of compatible substrates.

Keywords

• amination
• functionalization of alcohol
• metal-free
• s-(alkyl)thianthrenium salts
• thioetherification