HISTOPATHOLOGICAL CHANGES IN THE GUM EPITHELIUM OF PATIENTS WITH STOMACH ULCER

Abstract

This study aims to study the histopathological changes in the epithelium of the alveolar processes in patients with gastric ulcer. Material and methods. Gums bioptats in stomach ulcers patients have been studied, and 10 of them had chronic cataract and 8 had chronic periodontitis. The morphological structure after staining of paraffin sections was studied using traditional histological and histochemical methods. Also microscopic cytophotometry video was done. Results. Histopathological restructuring of the papillary and reticular zone of the lamina propria was detected, and also increasing number of microspaces between the basal and spine layers in epithelial cells causes growing hydrodynamic disorganization in microcirculation system. The research has led to the conclusion that gingival epithelium alteration in patients with peptic ulcer disease is a local demonstration the systemic immune response to contamination of the mucous membranes in gastrointestinal tract with Helicobacter pylori, and inflammatory-dystrophic changes in the overlying layers of epithelial cells are secondary.

Keywords

• h.pylori
• stomach ulcer
• chronic gingivitis