Open Medicine
(Sep 2020)
Glial cell induced neural differentiation of bone marrow stromal cells
Ma Qiang,
Cai Ming,
Shang Jing-Wei,
Yang Jun,
Gu Xin-Yi,
Liu Wen-Bo,
Yang Qing
Affiliations
Ma Qiang
School of Life Science and Biotechnology, Dalian University of Technology, No. 2 Linggong Road, Dalian 116023, Liaoning Province, China
Cai Ming
Department of Neurology, Affiliated Zhongshan Hospital of Dalian University, Dalian 116001, Liaoning Province, China
Shang Jing-Wei
Department of Neurology, Affiliated Zhongshan Hospital of Dalian University, Dalian 116001, Liaoning Province, China
Yang Jun
School of Life Science and Biotechnology, Dalian University of Technology, No. 2 Linggong Road, Dalian 116023, Liaoning Province, China
Gu Xin-Yi
Department of Neurology, Affiliated Zhongshan Hospital of Dalian University, Dalian 116001, Liaoning Province, China
Liu Wen-Bo
Department of Neurology, Affiliated Zhongshan Hospital of Dalian University, Dalian 116001, Liaoning Province, China
Yang Qing
School of Life Science and Biotechnology, Dalian University of Technology, No. 2 Linggong Road, Dalian 116023, Liaoning Province, China
DOI
https://doi.org/10.1515/med-2020-0229
Journal volume & issue
Vol. 15,
no. 1
Abstract
Read online
Bone marrow stromal cells (BMSCs) have an important application prospect in the field of cell therapy for various neurodegenerative diseases, and inducing factors that regulate BMSC differentiation are proposed as a promising therapeutic strategy. In this study, we explored the effect of glial cell-derived neurotrophic factor (GDNF) on the course of BMSC differentiation.
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