Indian Journal of Pathology and Microbiology (Jan 2016)

Lymphoblastic leukemia with surface light chain restriction: A diagnostic dilemma

  • Nikhil Rabade,
  • Asma Bibi,
  • Kiran Ghodke,
  • Nikhil Patkar,
  • Prashant Tembhare,
  • Pratibha Amare,
  • P G Subramanian,
  • Sumeet Gujral

DOI
https://doi.org/10.4103/0377-4929.188129
Journal volume & issue
Vol. 59, no. 3
pp. 410 – 412

Abstract

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Surface light chain expression is a feature of mature B-cell neoplasms. Light chain restriction in precursor B acute lymphoblastic leukemia is infrequently seen. We report a case of a 28-year-old female with non-FAB L3 morphology blasts and immunophenotypic features showing overlap between a precursor and mature B-cell neoplasm.

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