Role of transcription factor Cdx2 in the development of gastric intestinal metaplasia

Abstract

The role of intestinal differentiation transcription factor Cdx2 in the development of gastric intestinal metaplasia was established on the basis of its expression in material of gastric mucosa biopsies. Taking into account of CDX2 expression intensity the diagnostic algorithm of gastric intestinal metaplasia for further tactics of patients management was proposed.

Keywords

• intestinal differentiation transcription factor Cdx2
• intestinal metaplasia
• gastric mucosa