Emerging Infectious Diseases (Mar 2010)

Rare Influenza A (H3N2) Variants with Reduced Sensitivity to Antiviral Drugs

  • Clyde Dapat,
  • Yasushi Suzuki,
  • Reiko Saito,
  • Yadanar Kyaw,
  • Yi Yi Myint,
  • Nay Lin,
  • Htun Naing Oo,
  • Khin Yi Oo,
  • Ne Win,
  • Makoto Naito,
  • Go Hasegawa,
  • Isolde C. Dapat,
  • Hassan Zaraket,
  • Tatiana Baranovich,
  • Makoto Nishikawa,
  • Takehiko Saito,
  • Hiroshi Suzuki

DOI
https://doi.org/10.3201/eid1603.091321
Journal volume & issue
Vol. 16, no. 3
pp. 493 – 496

Abstract

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In 2007 and 2008 in Myanmar, we detected influenza viruses A (H3N2) that exhibited reduced sensitivity to both zanamivir and amantadine. These rare and naturally occurring viruses harbored a novel Q136K mutation in neuraminidase and S31N mutation in M2.

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