Optics (May 2023)

Advantages of a Photodiode Detector Endoscopy System in Fluorescence-Guided Percutaneous Liver Biopsies

  • Asier Marcos-Vidal,
  • Pedram Heidari,
  • Sheng Xu,
  • Bradford J. Wood,
  • Umar Mahmood

DOI
https://doi.org/10.3390/opt4020025
Journal volume & issue
Vol. 4, no. 2
pp. 340 – 350

Abstract

Read online

Image-guided liver biopsies can improve their success rate when combined with the optical detection of Indocyanine Green (ICG) fluorescence accumulated in tumors. Previous works used a camera coupled to a thin borescope to capture and quantify images from fluorescence emission during procedures; however, light-scattering prevented the formation of sharp images, and the time response for weakly fluorescent tumors was very low. Instead, replacing the camera with a photodiode detector shows an improved temporal resolution in a more compact and lighter device. This work presents the new design in a comparative study between both detection technologies, including an assessment of the temporal response and sensitivity to the presence of background fluorescence.

Keywords