Chronic wounds and diabetes mellitus: modern concept and prospects for conservative treatment

Abstract

Current trends in conservative therapy of chronic wounds associated with diabetes mellitus are discussed along with results of original studies aimedto assess efficacy of different methods for unloading the affected leg in patients with the neuropathic form of diabetic foot syndrome and diabeticnephropathy. Effects of collagen-containing dressings on the wound-related factors (matrix metalloproteinases 2 and 9, collagenolytic activity) andwound epithelization rate are described.

Keywords

• diabetes mellitus
• chronic wounds
• diabetic foot syndrome
• conservative treatment