COVID-19 MIS-C (Multisystem Inflammatory Syndrome in Children) Cases with Significant Echocardiographic Abnormality: A Case Series

Abstract

Post COVID-19 MIS-C cases are on the rise recently and various cardiac abnormalities are reported among them in different literature. Here we have presented six cases of MIS-C with significant echocardiographic abnormality. They have a varied presentation like acute encephalitis, acute renal failure, incomplete Kawasaki, shock or acute gastroenteritis along with fever. Our cases have raised inflammatory markers like ESR, CRP, IL-6 with increased D-dimer, CPK-MB and positive COVID serology. Except case5, none has any cardiovascular presentation but every case has some important echocardiographic finding. Mild pericardial effusion was present in two cases, gross LV systolic dysfunction with LVEF 40-45% in one case, significant coronary artery dilatation in three cases and valvular abnormality like MR or TR in three cases. So it is extremely important to evaluate every case of MIS-C with proper echocardiography even if they had no cardiac manifestation at presentation to prevent complication afterwards. Keywords: COVID -19, MIS-C, Echocardiography