Norepinephrine potentiates and serotonin depresses visual cortical responses by transforming eligibility traces

Su Z. Hong; Lukas Mesik; Cooper D. Grossman; Jeremiah Y. Cohen; Boram Lee; Hey-Kyoung Lee; Johannes W. Hell; Alfredo Kirkwood

doi:10.1038/s41467-022-30827-1

Nature Communications (Jun 2022)

Norepinephrine potentiates and serotonin depresses visual cortical responses by transforming eligibility traces

Su Z. Hong,
Lukas Mesik,
Cooper D. Grossman,
Jeremiah Y. Cohen,
Boram Lee,
Hey-Kyoung Lee,
Johannes W. Hell,
Alfredo Kirkwood

Affiliations

Su Z. Hong: Mind/Brain Institute, Johns Hopkins University
Lukas Mesik: Mind/Brain Institute, Johns Hopkins University
Cooper D. Grossman: Department of Neuroscience, Johns Hopkins University
Jeremiah Y. Cohen: Department of Neuroscience, Johns Hopkins University
Boram Lee: Department of Pharmacology, University of California at Davis
Hey-Kyoung Lee: Mind/Brain Institute, Johns Hopkins University
Johannes W. Hell: Department of Pharmacology, University of California at Davis
Alfredo Kirkwood: Mind/Brain Institute, Johns Hopkins University

DOI: https://doi.org/10.1038/s41467-022-30827-1
Journal volume & issue: Vol. 13, no. 1
pp. 1 – 12

Abstract

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Previous work has identified synaptic eligibility traces in slice preparations. Here the authors provide demonstration of eligibility traces in vivo during reinforcement learning.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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