대한영상의학회지 (Mar 2021)

Progressive Transformation of Germinal Centers in Axillary Lymph Nodes Mimicking Metastatic Lymphadenopathy after Breast Cancer Surgery: A Case Report

  • Sang Eun Park,
  • Kyu Ran Cho,
  • Sung Eun Song,
  • Ok Hee Woo,
  • Bo Kyoung Seo,
  • Jeonghyun Lee

DOI
https://doi.org/10.3348/jksr.2020.0106
Journal volume & issue
Vol. 82, no. 2
pp. 423 – 428

Abstract

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Progressive transformation of germinal centers (PTGC) is a rarely diagnosed, benign disease of the lymph nodes that commonly manifests as chronic lymphadenopathy. PTGC may be characterized by single or multiple non-tender lymph nodes, and it commonly involves the cervical, axillary, and inguinal areas. Although PTGC is identified with concurrent lymphoma in some patients, it is not considered as a premalignant entity. Histopathologic diagnosis of PTGC is rarely made, and imaging findings have been reported in very few studies. We present a case of PTGC that occurred at the contralateral axillary lymph nodes and mimicked metastatic lymphadenopathy after breast cancer surgery. We also discuss its imaging findings.

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