Nature Communications (Jan 2023)

Control of protein stability by post-translational modifications

  • Ji Min Lee,
  • Henrik M. Hammarén,
  • Mikhail M. Savitski,
  • Sung Hee Baek

DOI
https://doi.org/10.1038/s41467-023-35795-8
Journal volume & issue
Vol. 14, no. 1
pp. 1 – 16

Abstract

Read online

Here the authors summarize current knowledge of the regulation of protein stability by various post-translational modifications (PTMs) including methylation and phosphorylation. PTM-regulated degrons act as signals for protein degradation or stabilization.