Preoperative chemotherapy through intra-arterial combined with intra-venous administration in treatment of advanced gastric cancer

Abstract

Perioperative chemotherapy has been an important part of the comprehensive treatment of advanced gastric cancer. Different from the conventional systemic chemotherapy, preoperative chemotherapy through intra-arterial combined with intra-venous further optimized delivery routes according to characteristics of different drugs on the basis of combination chemotherapy，which has been studied and practiced at our center for more than 20 years. In this review, we will introduce this chemotherapy from the aspects of theoretical basis, development process, treatment advantages, and clinical research. The clinical efficacy and possible treatment mechanisms will be discussed through looking back on both clinic and basic study.

Keywords

• |preoperative chemotherapy through intra-arterial combined with intra-venous administration|advanced gastric cancer|intra-arterial chemotherapy|neoadjuvant chemotherapy