P543: TARGETING SAMHD1 WITH HYDROXYUREA IN FIRST-LINE CYTARABINE-BASED THERAPY OF NEWLY DIAGNOSED ACUTE MYELOID LEUKAEMIA: RESULTS FROM THE HEAT-AML TRIAL

• M. Jädersten,
• I. Lilienthal,
• N. Tsesmetzis,
• M. Lourda,
• S. Bengtzén,
• A. Bohlin,
• C. Arnroth,
• T. Erkers,
• B. Seashore-Ludlow,
• G. Giraud,
• G. S. Barkhordar,
• S. Tao,
• L. Fogelstrand,
• L. Saft,
• P. Östling,
• R. Schinazi,
• B. Kim,
• T. Schaller,
• G. Juliusson,
• S. Deneberg,
• S. Lehmann,
• G. Rassidakis,
• M. Höglund,
• J.-I. Henter,
• N. Herold

Affiliations

M. Jädersten

1 Department of Hematology, Karolinska University Hospital

I. Lilienthal

2 Childhood Cancer Research Unit

N. Tsesmetzis

2 Childhood Cancer Research Unit

M. Lourda

2 Childhood Cancer Research Unit

S. Bengtzén

3 Centre for hematology and regenerative medicine

A. Bohlin

3 Centre for hematology and regenerative medicine

C. Arnroth

4 Department of Oncology-Pathology, Karolinska Institutet, Stockholm

T. Erkers

4 Department of Oncology-Pathology, Karolinska Institutet, Stockholm

B. Seashore-Ludlow

4 Department of Oncology-Pathology, Karolinska Institutet, Stockholm

G. Giraud

5 Department of Immunology, Uppsala University, Uppsala

G. S. Barkhordar

6 Department of Clinical Genetics and Genomics, Sahlgrenska University Hospital, Gothenburg, Sweden

S. Tao

7 Department of Pediatrics, Emory University, Atlanta, United States of America

L. Fogelstrand

8 Department of Laboratory Medicine, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden

L. Saft

4 Department of Oncology-Pathology, Karolinska Institutet, Stockholm

P. Östling

4 Department of Oncology-Pathology, Karolinska Institutet, Stockholm

R. Schinazi

7 Department of Pediatrics, Emory University, Atlanta, United States of America

B. Kim

7 Department of Pediatrics, Emory University, Atlanta, United States of America

T. Schaller

9 Department of Infectious Diseases, University Hospital Heidelberg, Heidelberg, Germany

G. Juliusson

10 Department of Hematology, Skåne University Hospital, Lund

S. Deneberg

1 Department of Hematology, Karolinska University Hospital

S. Lehmann

11 Department of Medical Sciences, Uppsala University, Uppsala, Sweden

G. Rassidakis

4 Department of Oncology-Pathology, Karolinska Institutet, Stockholm

M. Höglund

11 Department of Medical Sciences, Uppsala University, Uppsala, Sweden

J.-I. Henter

2 Childhood Cancer Research Unit

N. Herold

2 Childhood Cancer Research Unit