mBio (Apr 2021)
Synthetic DNA Delivery of an Optimized and Engineered Monoclonal Antibody Provides Rapid and Prolonged Protection against Experimental Gonococcal Infection
- Elizabeth M. Parzych,
- Sunita Gulati,
- Bo Zheng,
- Mamadou A. Bah,
- Sarah T. C. Elliott,
- Jacqueline D. Chu,
- Nancy Nowak,
- George W. Reed,
- Frank J. Beurskens,
- Janine Schuurman,
- Peter A. Rice,
- David B. Weiner,
- Sanjay Ram
Affiliations
- Elizabeth M. Parzych
- Vaccine & Immunotherapy Center, The Wistar Institute of Anatomy and Biology, Philadelphia, Pennsylvania, USA
- Sunita Gulati
- Division of Infectious Diseases and Immunology, University of Massachusetts Medical School, Worcester, Massachusetts, USA
- Bo Zheng
- Division of Infectious Diseases and Immunology, University of Massachusetts Medical School, Worcester, Massachusetts, USA
- Mamadou A. Bah
- Vaccine & Immunotherapy Center, The Wistar Institute of Anatomy and Biology, Philadelphia, Pennsylvania, USA
- Sarah T. C. Elliott
- Vaccine & Immunotherapy Center, The Wistar Institute of Anatomy and Biology, Philadelphia, Pennsylvania, USA
- Jacqueline D. Chu
- Vaccine & Immunotherapy Center, The Wistar Institute of Anatomy and Biology, Philadelphia, Pennsylvania, USA
- Nancy Nowak
- Division of Infectious Diseases and Immunology, University of Massachusetts Medical School, Worcester, Massachusetts, USA
- George W. Reed
- Division of Infectious Diseases and Immunology, University of Massachusetts Medical School, Worcester, Massachusetts, USA
- Frank J. Beurskens
- Genmab, Utrecht, The Netherlands
- Janine Schuurman
- Division of Infectious Diseases and Immunology, University of Massachusetts Medical School, Worcester, Massachusetts, USA
- Peter A. Rice
- Division of Infectious Diseases and Immunology, University of Massachusetts Medical School, Worcester, Massachusetts, USA
- David B. Weiner
- Vaccine & Immunotherapy Center, The Wistar Institute of Anatomy and Biology, Philadelphia, Pennsylvania, USA
- Sanjay Ram
- Division of Infectious Diseases and Immunology, University of Massachusetts Medical School, Worcester, Massachusetts, USA
- DOI
- https://doi.org/10.1128/mBio.00242-21
- Journal volume & issue
-
Vol. 12,
no. 2
Abstract
Neisseria gonorrhoeae
