In vitro and in vivo datasets of topically applied ketorolac tromethamine in aqueous humor using Raman spectroscopy
Shuo Zhang,
Christian J.F. Bertens,
Roel J. Erckens,
Frank J.H.M. van den Biggelaar,
Tos T.J.M. Berendschot,
Carroll A.B. Webers,
Rudy M.M.A. Nuijts,
Marlies Gijs
Affiliations
Shuo Zhang
University Eye Clinic Maastricht, Maastricht University Medical Center+, P. Debyelaan 25, P.O. Box 5800, 6202, AZ, Maastricht, the Netherlands; Maastricht University, School for Mental Health and Neuroscience, University Eye Clinic Maastricht, Universiteitssingel 50, P.O. Box 616, 6200, MD, Maastricht, the Netherlands
Christian J.F. Bertens
University Eye Clinic Maastricht, Maastricht University Medical Center+, P. Debyelaan 25, P.O. Box 5800, 6202, AZ, Maastricht, the Netherlands; Maastricht University, School for Mental Health and Neuroscience, University Eye Clinic Maastricht, Universiteitssingel 50, P.O. Box 616, 6200, MD, Maastricht, the Netherlands; Chemelot Institute for Science and Technology (InSciTe), Urmonderbaan 20F, 6167, RD, Geleen, the Netherlands; Corresponding author. University Eye Clinic Maastricht, Maastricht University Medical Center+, P.O. Box 5800, 6202, AZ, Maastricht, the Netherlands.
Roel J. Erckens
University Eye Clinic Maastricht, Maastricht University Medical Center+, P. Debyelaan 25, P.O. Box 5800, 6202, AZ, Maastricht, the Netherlands; Department of Ophthalmology, Zuyderland Medical Center, Heerlen, the Netherlands
Frank J.H.M. van den Biggelaar
University Eye Clinic Maastricht, Maastricht University Medical Center+, P. Debyelaan 25, P.O. Box 5800, 6202, AZ, Maastricht, the Netherlands; Maastricht University, School for Mental Health and Neuroscience, University Eye Clinic Maastricht, Universiteitssingel 50, P.O. Box 616, 6200, MD, Maastricht, the Netherlands; Chemelot Institute for Science and Technology (InSciTe), Urmonderbaan 20F, 6167, RD, Geleen, the Netherlands
Tos T.J.M. Berendschot
University Eye Clinic Maastricht, Maastricht University Medical Center+, P. Debyelaan 25, P.O. Box 5800, 6202, AZ, Maastricht, the Netherlands; Maastricht University, School for Mental Health and Neuroscience, University Eye Clinic Maastricht, Universiteitssingel 50, P.O. Box 616, 6200, MD, Maastricht, the Netherlands
Carroll A.B. Webers
University Eye Clinic Maastricht, Maastricht University Medical Center+, P. Debyelaan 25, P.O. Box 5800, 6202, AZ, Maastricht, the Netherlands; Maastricht University, School for Mental Health and Neuroscience, University Eye Clinic Maastricht, Universiteitssingel 50, P.O. Box 616, 6200, MD, Maastricht, the Netherlands
Rudy M.M.A. Nuijts
University Eye Clinic Maastricht, Maastricht University Medical Center+, P. Debyelaan 25, P.O. Box 5800, 6202, AZ, Maastricht, the Netherlands; Maastricht University, School for Mental Health and Neuroscience, University Eye Clinic Maastricht, Universiteitssingel 50, P.O. Box 616, 6200, MD, Maastricht, the Netherlands; Chemelot Institute for Science and Technology (InSciTe), Urmonderbaan 20F, 6167, RD, Geleen, the Netherlands; Department of Ophthalmology, Zuyderland Medical Center, Heerlen, the Netherlands
Marlies Gijs
University Eye Clinic Maastricht, Maastricht University Medical Center+, P. Debyelaan 25, P.O. Box 5800, 6202, AZ, Maastricht, the Netherlands; Maastricht University, School for Mental Health and Neuroscience, University Eye Clinic Maastricht, Universiteitssingel 50, P.O. Box 616, 6200, MD, Maastricht, the Netherlands; Chemelot Institute for Science and Technology (InSciTe), Urmonderbaan 20F, 6167, RD, Geleen, the Netherlands
This article includes datasets acquired by Raman spectroscopy from in vivo and in vitro ocular samples collected from the dataset from Bertens and Zhang et al., “Confocal Raman spectroscopy: Evaluation of a non-invasive technique for the detection of topically applied ketorolac tromethamine in vitro and in vivo” (Bertens and Zhang, et al.). Detection of ketorolac tromethamine in pig eyes was performed in vitro and rabbit eyes in vivo. Extracted aqueous humor samples from pig and rabbit eyes were measured in vitro using a cuvette. This manuscript shows the spectral Raman data without pre-treatment or analysis from ocular tissues and provides further information towards aqueous humor research via alternative data processing methods. Furthermore, the raw data enclosed may be used for future aqueous humor investigations and pharmaceutical research. Keywords: Raman spectroscopy, Ophthalmology, Ketorolac tromethamine, Rabbits, Aqueous humor, Pig eyes
