Детские инфекции (Москва) (Aug 2015)

EFFECT OF PROBIOTIC WITH LACTOBACILLUS IN CHILDREN WITH INFECTIOUS DISEASES RECEIVING ANTIBACTERIAL THERAPY

  • O. V. Kladova,
  • O. V. Molochkova,
  • L. A. Pronina,
  • L. V. Glazunova,
  • T. V. Agafonova,
  • N. N. Shevchenko,
  • I. M. Donin,
  • V. D. Rusakova

DOI
https://doi.org/10.22627/2072-8107-2013-12-3-56-61
Journal volume & issue
Vol. 12, no. 3
pp. 56 – 61

Abstract

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For specification incidence of antibiotic-associated diarrhea in children under 3 years and older treated with antibiotics, used the method of open prospective comparative clinical study. 170 patients (the basic group — 105 patients receiving probiotic with Lactobacillus, the control group — 65 patients) aged from 3 months to 15 years with acute infectious diseases receiving antibacterial therapy for not less than 3 days and examined in hospital conditions were included in the study. As a result the rate of antibiotics-associated diarrhea in children constitued 85% in children younger than 3 years and 25% in children of higher age. Preventive application of probiotic with Lactobacillus allows to decrease the rate of occurrence of antibiotics-associated diarrhea in children as well as the duration of diarrhea syndrome.

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