mSystems (Aug 2021)
Adenovirus Remodeling of the Host Proteome and Host Factors Associated with Viral Genomes
- Joseph M. Dybas,
- Krystal K. Lum,
- Katarzyna Kulej,
- Emigdio D. Reyes,
- Richard Lauman,
- Matthew Charman,
- Caitlin E. Purman,
- Robert T. Steinbock,
- Nicholas Grams,
- Alexander M. Price,
- Lydia Mendoza,
- Benjamin A. Garcia,
- Matthew D. Weitzman
Affiliations
- Joseph M. Dybas
- ORCiD
- Division of Protective Immunity and Division of Cancer Pathobiology, The Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, USA
- Krystal K. Lum
- Division of Protective Immunity and Division of Cancer Pathobiology, The Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, USA
- Katarzyna Kulej
- Division of Protective Immunity and Division of Cancer Pathobiology, The Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, USA
- Emigdio D. Reyes
- Division of Protective Immunity and Division of Cancer Pathobiology, The Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, USA
- Richard Lauman
- Department of Biochemistry and Biophysics, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA
- Matthew Charman
- Division of Protective Immunity and Division of Cancer Pathobiology, The Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, USA
- Caitlin E. Purman
- Division of Protective Immunity and Division of Cancer Pathobiology, The Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, USA
- Robert T. Steinbock
- Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA
- Nicholas Grams
- Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA
- Alexander M. Price
- Division of Protective Immunity and Division of Cancer Pathobiology, The Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, USA
- Lydia Mendoza
- Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA
- Benjamin A. Garcia
- Department of Biochemistry and Biophysics, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA
- Matthew D. Weitzman
- ORCiD
- Division of Protective Immunity and Division of Cancer Pathobiology, The Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, USA
- DOI
- https://doi.org/10.1128/mSystems.00468-21
- Journal volume & issue
-
Vol. 6,
no. 4
Abstract
Viral infections induce myriad changes to the host cell proteome. As viruses harness cellular processes and counteract host defenses, they impact abundance, posttranslational modifications, interactions, or localization of cellular proteins.