Brazilian Journal of Oncology (Apr 2023)
Key issues in the management of cervical cancer: consensus recommendations by a Brazilian expert panel
- Eduardo Paulino,
- Glauco Baiocchi,
- Agnaldo Lopes Silva,
- Aknar Calabrich,
- Andre Lopes,
- Andrea Paiva Gadelha Guimarães,
- Andreia Cristina Melo,
- Angelica Nogueira-Rodrigues,
- Carla Rameri Azevedo,
- Carlos Eduardo da Cunha Mattos Andrade,
- Daniele Xavier Assad,
- Denise Ferreira Silva Alves,
- Diocesio Alves Pinto Andrade,
- Éder Babygton Alves,
- Georgia Fontes Cintra,
- Gustavo Guitmann,
- Flavia Carolina Grosso Gabrielli,
- Marcelo Andrade Vieira,
- Mariana Scaranti,
- Michael Jenwei Chen,
- Paulo Henrique Zanvettor,
- Rachele Grazziotin Reisner,
- Renato Jose Affonso,
- Renato Moretti-Marques,
- Ronaldo Pereira Souza,
- Samantha Cabral Severino Costa,
- Thales Paulo Batista,
- Fernando Cotait Maluf
Affiliations
- Eduardo Paulino
- EVA - Brazilian Gynecologic Oncology Group - São Paulo - SP - Brazil.
- Glauco Baiocchi
- EVA - Brazilian Gynecologic Oncology Group - São Paulo - SP - Brazil.
- Agnaldo Lopes Silva
- EVA - Brazilian Gynecologic Oncology Group - São Paulo - SP - Brazil.
- Aknar Calabrich
- EVA - Brazilian Gynecologic Oncology Group - São Paulo - SP - Brazil.
- Andre Lopes
- EVA - Brazilian Gynecologic Oncology Group - São Paulo - SP - Brazil.
- Andrea Paiva Gadelha Guimarães
- EVA - Brazilian Gynecologic Oncology Group - São Paulo - SP - Brazil.
- Andreia Cristina Melo
- EVA - Brazilian Gynecologic Oncology Group - São Paulo - SP - Brazil.
- Angelica Nogueira-Rodrigues
- EVA - Brazilian Gynecologic Oncology Group - São Paulo - SP - Brazil.
- Carla Rameri Azevedo
- EVA - Brazilian Gynecologic Oncology Group - São Paulo - SP - Brazil.
- Carlos Eduardo da Cunha Mattos Andrade
- EVA - Brazilian Gynecologic Oncology Group - São Paulo - SP - Brazil.
- Daniele Xavier Assad
- EVA - Brazilian Gynecologic Oncology Group - São Paulo - SP - Brazil.
- Denise Ferreira Silva Alves
- EVA - Brazilian Gynecologic Oncology Group - São Paulo - SP - Brazil.
- Diocesio Alves Pinto Andrade
- EVA - Brazilian Gynecologic Oncology Group - São Paulo - SP - Brazil.
- Éder Babygton Alves
- EVA - Brazilian Gynecologic Oncology Group - São Paulo - SP - Brazil.
- Georgia Fontes Cintra
- EVA - Brazilian Gynecologic Oncology Group - São Paulo - SP - Brazil.
- Gustavo Guitmann
- EVA - Brazilian Gynecologic Oncology Group - São Paulo - SP - Brazil.
- Flavia Carolina Grosso Gabrielli
- Instituto do Câncer do Estado de São Paulo - ICESP, Radiation Oncology - São Paulo - SP - Brazil.
- Marcelo Andrade Vieira
- EVA - Brazilian Gynecologic Oncology Group - São Paulo - SP - Brazil.
- Mariana Scaranti
- EVA - Brazilian Gynecologic Oncology Group - São Paulo - SP - Brazil.
- Michael Jenwei Chen
- EVA - Brazilian Gynecologic Oncology Group - São Paulo - SP - Brazil.
- Paulo Henrique Zanvettor
- EVA - Brazilian Gynecologic Oncology Group - São Paulo - SP - Brazil.
- Rachele Grazziotin Reisner
- EVA - Brazilian Gynecologic Oncology Group - São Paulo - SP - Brazil.
- Renato Jose Affonso
- EVA - Brazilian Gynecologic Oncology Group - São Paulo - SP - Brazil.
- Renato Moretti-Marques
- EVA - Brazilian Gynecologic Oncology Group - São Paulo - SP - Brazil.
- Ronaldo Pereira Souza
- EVA - Brazilian Gynecologic Oncology Group - São Paulo - SP - Brazil.
- Samantha Cabral Severino Costa
- EVA - Brazilian Gynecologic Oncology Group - São Paulo - SP - Brazil.
- Thales Paulo Batista
- EVA - Brazilian Gynecologic Oncology Group - São Paulo - SP - Brazil.
- Fernando Cotait Maluf
- EVA - Brazilian Gynecologic Oncology Group - São Paulo - SP - Brazil.
- DOI
- https://doi.org/10.5935/2526-8732.20230394
- Journal volume & issue
-
Vol. 19
Abstract
Objective: We report the results of a panel of Brazilian experts and provide recommendations for the management of these patients. Material and Methods: The panel convened composed by 28 local opinion leaders, addressed 59 multiple-choice questions taking into account the published scientific literature and their own clinical experience. The level of agreement among panel members was qualified as (1) consensus, when at least 75% of the voting panel members; (2) majority vote (50%-74.9%); or (3) less than majority vote. Results: There was at least majority vote for eight of 10 questions on staging and follow-up; for 14 of 23 questions on the treatment of early-stage disease; for 12 of 14 questions related to the treatment of locally-advanced disease; and for seven of the 12 questions related to the treatment of recurrent/metastatic disease. Conclusion: The current recommendations may help practitioners from Brazil and other countries to improve the care they provide to patients.
Keywords
- chemoradiotherapy
- gynecologic surgical procedures
- immune checkpoint inhibitors
- platinum compounds
- uterine cervical neoplasms