Nature Communications (Oct 2024)
Strengthening and expanding capacities in clinical trials: advancing pandemic prevention, preparedness and response in Africa
- Nicaise Ndembi,
- Tadesse T. Mekonen,
- Morenike Oluwatoyin Folayan,
- Nebiyu Dereje,
- Adriaan Kruger,
- Joseph Fokam,
- Elvis Temfack,
- Tajudeen Raji,
- Jean Nachega,
- Yap Boum,
- Trevor A. Crowell,
- Alain Ngashi Ngongo,
- Souleymane Mboup,
- Francine Ntoumi,
- Glaudina Loots,
- Michael Makanga,
- Samba Sow,
- Salim Abdool Karim,
- John Nkengasong
Affiliations
- Nicaise Ndembi
- Africa Centres for Disease Control and Prevention (Africa CDC), Haile Garment Square
- Tadesse T. Mekonen
- Avacare Health, Grand bay
- Morenike Oluwatoyin Folayan
- Department of Child Dental Health, Obafemi Awolowo University
- Nebiyu Dereje
- Africa Centres for Disease Control and Prevention (Africa CDC), Haile Garment Square
- Adriaan Kruger
- Nuvoteq, Hazelwood Incubator, 47 Hazelwood Rd, Hazelwood
- Joseph Fokam
- Chantal BIYA International Reference Centre for Research on HIV/AIDS Prevention and Management
- Elvis Temfack
- Africa Centres for Disease Control and Prevention (Africa CDC), Haile Garment Square
- Tajudeen Raji
- Africa Centres for Disease Control and Prevention (Africa CDC), Haile Garment Square
- Jean Nachega
- Stellenbosch University, Faculty of Medicine and Health Sciences
- Yap Boum
- Institut Pasteur de
- Trevor A. Crowell
- Henry M. Jackson Foundation for the Advancement of Military Medicine
- Alain Ngashi Ngongo
- Africa Centres for Disease Control and Prevention (Africa CDC), Haile Garment Square
- Souleymane Mboup
- Institut de Recherche en Santé, de Surveillance Épidémiologique et de Formations (IRESSEF)
- Francine Ntoumi
- Fondation Congolaise pour la Recherche Médicale, Republic of Congo and Institute of Tropical Medicine, University of Tübingen
- Glaudina Loots
- Department of Science and Technology
- Michael Makanga
- Global Health EDCTP3 Joint Undertaking
- Samba Sow
- Center for Vaccine Development (CVD) at the Mali Ministry of Health and Social Development
- Salim Abdool Karim
- Centre for the AIDS Programme of Research in South Africa (CAPRISA), Durban and Mailman School of Public Health, Columbia University
- John Nkengasong
- Bureau of Global Health Security and Diplomacy, President’s Emergency Plan for AIDS Relief
- DOI
- https://doi.org/10.1038/s41467-024-53126-3
- Journal volume & issue
-
Vol. 15,
no. 1
pp. 1 – 6
Abstract
Enhancing the clinical trial capabilities within Africa is essential to augment the continent’s pandemic prevention, preparedness and response efforts. Here, we describe the critical challenges of clinical trials in Africa and draw upon the lessons learnt from the Consortium for COVID-19 Vaccine Clinical Trials (CONCVACT) experience, such as the importance of regional collaboration, capacity building and establishing standardized protocols.
