Current Directions in Biomedical Engineering (Sep 2019)

Numerical simulation and in vitro examination of the flow behaviour within coronary stents

  • Melzer Helena-Sophie,
  • Ahrens Ralf,
  • Guber Andreas E.,
  • Dohse Jakob

DOI
https://doi.org/10.1515/cdbme-2019-0136
Journal volume & issue
Vol. 5, no. 1
pp. 541 – 544

Abstract

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This paper discusses the influence of different design parameters of stents by mathematical flow simulations and flow measurements using micro-particle image velocimetry (micro-PIV). A stent strut may cause recirculation areas, which are considered to be the source of thrombosis and the process of in-stent restenosis. The simulations showed that a reduced strut height and a chamfering of the struts reduce these recirculation zones. The numerically determined results were compared with experimental investigations. For this purpose metallic stent structures were transferred into transparent channel systems made of PDMS. The experimental investigations confirm the results of numerical simulations.

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