Memorias do Instituto Oswaldo Cruz (Dec 2012)

Genotyping of gastroenteric viruses in hospitalised children: first report of norovirus GII.21 in Brazil

  • Mônica Simões Rocha Ferreira,
  • Rita de Casia Cubel Garcia,
  • Maria da Penha Trindade Pinheiro Xavier,
  • Rubia Lane Ribeiro,
  • Rosane Maria Assis,
  • Maria do Céu MS Mota,
  • José Paulo Gagliardi Leite,
  • Marize Pereira Miagostovich,
  • Solange Artimos de Oliveira

DOI
https://doi.org/10.1590/S0074-02762012000800017
Journal volume & issue
Vol. 107, no. 8
pp. 1064 – 1067

Abstract

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This retrospective study (April-September 2003) was designed to investigate the roles of the main viruses responsible for cases of acute infantile gastroenteritis in hospitalised children up to two years of age. The viruses were identified in 64.7% (88/136) of the cases and the detection rates of rotavirus A (RVA), norovirus (NoV) and astrovirus were 41.9% (57/136), 30.3% (24/79) and 12.7% (7/55), respectively. RVA and NoV were detected in 20 of the 24 reported nosocomial infection cases. This study identified the first circulation of the genotype NoV GII.21 in Brazil and highlights the need to establish differential diagnoses through active laboratorial surveillance.

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