Frontiers in Pharmacology (Nov 2021)

Advantages of Tailored Isotretinoin Treatment in Moderate to Severe Acne: Real-Life Data

  • Nevena Skroza,
  • Ersilia Tolino,
  • Veronica Balduzzi,
  • Nicoletta Bernardini,
  • Alessandra Mambrin,
  • Anna Marchesiello,
  • Federica Marraffa,
  • Giovanni Rossi,
  • Salvatore Volpe,
  • Ilaria Proietti,
  • Concetta Potenza

DOI
https://doi.org/10.3389/fphar.2021.733526
Journal volume & issue
Vol. 12

Abstract

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This retrospective single-center study analyzes the efficacy and safety of isotretinoin for the treatment of moderate to severe acne in real-life clinical practice, particularly with regard to acne severity, isotretinoin cumulative dosage, and patients’ gender. The results suggest the opportunity of an early isotretinoin systemic treatment in patients affected by moderate acne and emphasize the importance of an appropriate dose adjustment in order to minimize adverse events.

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